HA booster - 汇融科技

So simple, so perfect

Looking for the perfect hyaluronic acids？

Here's the answer

37.5mg pure HA

Simplify the hydrating process

Learn about HA

Hyaluronic acid (HA) is a linear macromolecular acidic mucopolysaccharide widely distributed in human and animals. In 1934, Professor Meyer of Columbia University isolated hyaluronic acid from bovine vitreous, and then Kendell extracted hyaluronic acid from fermentation broth in 1937. Today, the output of hyaluronic acid raw materials in China has ranked among the top in the world.

HA consists of glucuronic acid and acetylglucosamine. It exists in extracellular matrix, especially in dermis and epidermis. Unlike other glucosaminoglycans, HA is not synthesized in the endoplasmic reticulum, but by three subtypes of hyaluronate synthase in the cytoplasm on the surface of cell membrane.

HA is widely distributed in nature. In vivo, more than 50% of hyaluronic acid exists in skin, lung and intestine. In early studies, the main source of hyaluronic acid was umbilical cord. At present, HA can be extracted from animal tissues, such as chicken crowns, eye vitreous bodies, brain cartilage and joint fluid, and can also be fermented by bacteria.

Simple

so the best

Simple

but difficult

High concentration filling

Exquisite, and competitive

This product adopts the formula suitable for Asian skin, mainly macromolecular HA to increase the hydrating effect. HA is an important component of extracellular matrix (ECM), regulating the behavior of cells, thus affecting the state of the skin. Exogenous HA can promote cells in the wound area to express relevant factors to heal faster.

In order to refine HA molecules, we invented CRYOTEK® Purify - a system that maintains the stability and viscosity of HA molecules. Our HA matches with various meso-therapy devices without common leakage. This liquidity is also attributed to by engineers at HEROSTEM® LAB thanks to their hundreds of experiments. We believe that the existing formula takes into account four aspects: pain, colliculus absorption, leakage loss and hydration effect.

Science in hydrating

See formula details

Viscosity up to 80000 cP

Prolonged treatment effects up to 50%+

HA molecules form a rigid helical column in space, and the inner side of the column has strong hydrophilicity. The solution has good viscoelasticity and osmotic pressure, that is, water molecules are combined with HA molecules through polar bonds and hydrogen bonds in the HA molecular network, so that water molecules are fixed in the column and stay stable. HA has very strong water absorption capacity, which helps it absorb 1000 times of water of its own mass.

1000X hydrating

away from dry skin

One ion

to fix them all

Each disaccharide unit on HA molecular chain has a negative charge, which helps it interact with ion. HA helps adjust the flow and concentration of cations around cells, change the diffusion rate of substances in the skin, and participate in the transportation of water and electrolyte.

HA also helps maintain the normal permeability of the arterial wall. it can significantly increase the permeability to improve the capillary blood circulation, keep the skin healthy, and improve the adaptability of the skin to the changes of the external environment.

The extraordinary one

Through research, we found that high molecular weight HA (greater than 1800kd) helps prevent skin dehydration. It has certain permeability only at the stratum corneum. Once it enters the epidermis, it is easy to protect cells. Therefore, HA is also an important component of extracellular matrix (ECM), affecting and regulating the behavior of skin cells.

Among the existing hydrating products, greater molecule weights produce longer-lasting hydration effect. However, the ultimate sterilization process often leads to the destruction of molecular bonds and the degradation of HA. Increasing the HA concentration can hedge the loss of HA caused by sterilization, also increasing the difficulty of production at the same time. Engineers at HEROSTEM® Lab invented new purify system - CRYOTEK® Purify. With CRYOTEK® we are finally able to completely retain the HA structure in the production process and eliminate the problem of molecular chain fracture.

Small, but BIG

CRYOTEK® Purify protects HA molecule from the influence of sterilization. With the new system, we proudly present our HA booster - CRYOCELL®. The product has longer-lasting hydrating effect. The perfectly retained macromolecular HA will be gradually hydrolyzed by enzyme in vivo, and more hydrophilic groups are released to prolong the effect duration of the product.

CRYOCELL

See our case

Application

Cautions

·Take one solution with meso-therapy every 3 months;

·Use hydrating mask before and after.

·Clean face before the treatment;

·Do not use twice after opening the vial；

·Do not use if solution appears unclear and non-transparent；

·Store at room temperature;

·Avoid laser-like treatment on the same day.

Specification
Q&A

Composition

Hyaluronic Acid

Cat. No.

MDHA02

2.5g

Specs

Viscosity

80000 cP

Molecule Weight

Approximately 140 kD

Storage

Room temperature

Purity

> 95 % by SDS-PAGE analyses. > 95 % by HPLC analyses.

Endotoxines

< 0.01 EU/mg

Usage

This GMP product can be for research use or further manufacturing use.

Appearance

Colorless

Viscosity

80000 cP

What products can CRYOCELL combine with?

Whitening: 0.5mL VC;

Anti-aging: 2-3mL PN, FILORGA or other products with similar functions;

Refining: 2mL Tranexamic acid (0.1g/mL)

What are the possible side effects?

Dryness, slight rash, redness, swelling and bruise are common side effects, which will fade within 2-3 days after operation. It is recommended to apply medical mask after the therapy;

In case of inflammatory reaction or other side effects lasting for more than one week, please consult with your dermatologist immediately.

Specification

COMPOSITION	HYALURONIC ACID
CAT.NO	MDHA02
SPECS	2.5g
PURITY	> 95 % BY SDS-PAGE ANALYSES. > 95 % BY HPLC ANALYSES.
MOLECULE WEIGHT	APPROX. 140kD
VISCOSITY	APPROX. 80000 cP
ENDOTOXINES	< 0.01EU/MG
APPEARENCES	COLORLESS
USAGE	FOR RESEARCH OR FURTHER MANUFACTURE USE
STORAGE	ROOM TEMPERATURE

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